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Article

ARNTL (BMAL1) and NPAS2 gene variants contribute to fertility and seasonality.

PloS one - 2 Apr 2010

Kovanen Leena, Saarikoski Sirkku T, Aromaa Arpo, Lönnqvist Jouko, Partonen Timo

Abstract excerpt

BACKGROUND: Circadian clocks guide the metabolic, cell-division, sleep-wake, circadian and seasonal cycles. Abnormalities in these clocks may be a health hazard. Circadian clock gene polymorphisms have been linked to sleep, mood and metabolic disorders. Our study aimed to examine polymorphisms in...

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Source

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Identifiers

PMID: 20368993
DOI: 10.1371/journal.pone.0010007
PMCID: PMC2848852

Genes

NPAS2
BMAL1
CLOCK

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20368993-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Common genetic variants in ARNTL and NPAS2 and at chromosome 12p13 are associated with objectively measured sleep traits in the elderly.Semantic proximity Read ↗

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