Article
Effect of classifying disease states in genetic association studies for paratuberculosis.
Preventive veterinary medicine - 1 Jun 2010
Osterstock J B, Sinha S, Seabury C M, Cohen N D
Abstract excerpt
Genetic association studies are a means to elucidate underlying genetic regulation of host-pathogen interaction, immune response, and the fate of infection. Diseases such as paratuberculosis in cattle lack definitive diagnostic criteria, thereby complicating the definition of infection status as an outcome for genetic association studies. A study was performed to evaluate the potential bias in estimates of effect...
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