Article
Advances in understanding the genetic architecture of antibody response to paratuberculosis in sheep by heritability estimate and LDLA mapping analyses and investigation of candidate regions using sequence-based data.
Genetics, selection, evolution : GSE - 10 Jan 2024
Usai Mario Graziano, Casu Sara, Sechi Tiziana, Salaris Sotero L, Miari Sabrina, Mulas Giuliana, Cancedda Maria Giovanna, Ligios Ciriaco, Carta Antonello
Abstract excerpt
BACKGROUND: Paratuberculosis is a contagious and incurable disease that is caused by Mycobacterium avium subsp. paratuberculosis (MAP) with significant negative effects on animal welfare and farm profitability. Based on a large naturally infected flock over 12 years, we analyzed repeated enzyme-linked immunosorbent assay tests (ELISA), OvineSNP50 BeadChip genotypes and whole-genome sequences imputed from 56...
Topics
- Animals
- Sheep
- Antibody Formation
- Paratuberculosis
- Genotype
- Antibodies
- Enzyme-Linked Immunosorbent Assay