Article
LCT-13910C>T polymorphism-associated lactose malabsorption and risk for colorectal cancer in Italy.
Digestive and liver disease : official journal of the Italian Society of Gastroenterology and the Italian Association for the Study of the Liver - 1 Oct 2010
Tarabra Elena, Pazienza Paola, Borghesio Elisabetta, Actis Giovanni C, Tappero Gianfranco, Framarin Luciana, Ayoubi Mohammad, Castellino Francesca, Leone Nicola, Sansoè Giovanni, De Paolis Paolo, Comandone Alessandro, Rosina Floriano
Abstract excerpt
BACKGROUND: The activity of epithelial lactase (LCT) associates with a polymorphism 13910 bp upstream the LCT-encoding gene (LCT-13910C>T). The relationship between LCT-13910C>T polymorphism and risk for colorectal cancer is unclear. AIMS: We examined the relationship between the LCT-13910C>T polymorphism causing lactose intolerance and risk for colorectal cancer/polyps onset in the Italian population. PATIENTS...
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