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Article

Mitochondrial mutagenesis induced by tumor-specific radiation bystander effects.

Journal of molecular medicine (Berlin, Germany) - 1 Jul 2010

Gorman Sheeona, Fox Edward, O'Donoghue Diarmuid, Sheahan Kieran, Hyland John, Mulcahy Hugh, Loeb Lawrence A, O'Sullivan Jacintha

Abstract excerpt

The radiation bystander effect is a cellular process whereby cells not directly exposed to radiation display cellular alterations similar to directly irradiated cells. Cellular targets including mitochondria have been postulated to play a significant role in this process. In this study, we utilized the Random Mutation Capture assay to quantify the levels of random mutations and deletions in the mitochondrial...

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Source

Identifiers

PMID: 20349220
DOI: 10.1007/s00109-010-0616-3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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