Article
Mutations in hepatitis C virus genotype 1b and the sensitivity of interferon-ribavirin therapy after liver transplantation.
Journal of hepatology - 1 May 2010
Fukuhara Takasuke, Taketomi Akinobu, Okano Shinji, Ikegami Toru, Soejima Yuji, Shirabe Ken, Maehara Yoshihiko
Abstract excerpt
BACKGROUND & AIMS: The results of post-transplant antiviral therapy for recurrent hepatitis C virus (HCV) are poor, and significant pre-transplant predictors for sustained viral response (SVR) have not yet been identified. METHODS: Pegylated interferon/ribavirin therapy was performed for more than 48 weeks in 50 patients who underwent liver transplantation (LT) for HCV genotype 1-related liver disease. Of these,...
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