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Interleukin-22 genetic polymorphisms and risk of colon cancer.

Cancer causes & control : CCC - 1 Aug 2010

Thompson Cheryl L, Plummer Sarah J, Tucker Thomas C, Casey Graham, Li Li

Abstract excerpt

Interleukin-22 (IL-22) is a member of the IL-10 family of anti-inflammatory cytokines that mediates epithelial immunity. IL-22 expression is enhanced in inflamed colon mucosa in individuals with inflammatory bowel disease. We carried out an association study to examine the hypothesis that common variation in the IL-22 gene is associated with risk of colon cancer. Seven tagging SNPs were genotyped in 561 colon...

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PMID: 20339910
DOI: 10.1007/s10552-010-9542-5

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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