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Article

Identification of novel pneumolysin alleles from paediatric carriage isolates of Streptococcus pneumoniae.

Journal of medical microbiology - 1 Jul 2010

Jefferies J M C, Tocheva A S, Rubery H, Bennett J, Garland J, Christodoulides M, Faust S N, Smith A, Mitchell T J, Clarke S C

Abstract excerpt

Pneumolysin (Ply) is a major virulence factor of Streptococcus pneumoniae and is produced by all known clinical isolates of pneumococci. Pneumolysin toxoids are being considered as vaccine candidates. We investigated the diversity of pneumolysin among 194 nasopharyngeal pneumococci characterized...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20339017
DOI: 10.1099/jmm.0.018663-0

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20339017-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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