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Article

Periovulatory expression of hyaluronan and proteoglycan link protein 1 (Hapln1) in the rat ovary: hormonal regulation and potential function.

Molecular endocrinology (Baltimore, Md.) - 1 Jun 2010

Liu Jing, Park Eun-Sil, Curry Thomas E, Jo Misung

Abstract excerpt

Periovulatory follicular matrix plays an important role in cumulus-oocyte complex (COC) expansion, ovulation, and luteal formation. Hyaluronan and proteoglycan link protein 1 (HAPLN1), a component of follicular matrix, was shown to enhance COC expansion in vitro. However, the regulatory mechanisms of periovulatory expression of Hapln1 and its role in periovulatory granulosa cells have not been elucidated. We...

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Source

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Identifiers

PMID: 20339004
DOI: 10.1210/me.2009-0325
PMCID: PMC2875804

Genes

HAPLN1
RUNX1
RUNX2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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