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hUMSC transplantation restores follicle development in ovary damaged mice via re-establish extracellular matrix (ECM) components

24 Aug 2023

Abstract excerpt

OBJECTIVES: Explore the therapeutic role of human umbilical mesenchymal stem cells (hUMSCs) transplantation for regeneration of ECM components and restoration of follicular development in mice. BACKGROUND: The extracellular matrix (ECM) is crucial to maintain ovary function and regulate follicular development, as it participates in important cell signaling and provides physical support to the cells. However, it...

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PMID: 37620943
DOI: 10.1186/s13048-023-01217-y

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