Article
Common germ-line polymorphism of C1QA and breast cancer survival.
British journal of cancer - 13 Apr 2010
Azzato E M, Lee A J X, Teschendorff A, Ponder B A J, Pharoah P, Caldas C, Maia A T
Abstract excerpt
BACKGROUND: A synonymous single nucleotide polymorphism (SNP) rs172378 (A>G, Gly->Gly) in the complement component C1QA has been proposed to be associated with distant breast cancer metastasis. We previously reported overexpression of this gene to be significantly associated with better prognosis in oestrogen-receptor-negative tumours. The purpose of this study was to investigate the association of rs172378 with...
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