Article
The pattern of clinical breast cancer metastasis correlates with a single nucleotide polymorphism in the C1qA component of complement.
Immunogenetics - 1 Feb 2006
Racila Emilian, Racila Doina M, Ritchie Justine M, Taylor Christiana, Dahle Christopher, Weiner George J
Abstract excerpt
Complement is one of primary defense mechanisms against intravascular microorganisms and could play a role in the immune response to malignancy and hence its clinical behavior. We evaluated if the sole coding polymorphism of C1qA associates with outcome in patients with breast carcinoma. Genotyping for C1qA[276A/G] was performed in 63 breast cancer subjects with localized tumor and compared with that in 38 breast...
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