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Article

Haplotype-based pharmacogenetic analysis for longitudinal quantitative traits in the presence of dropout.

Journal of biopharmaceutical statistics - 1 Mar 2010

Tzeng Jung-Ying, Lu Wenbin, Farmen Mark W, Liu Youfang, Sullivan Patrick F

Abstract excerpt

We propose a variety of methods based on the generalized estimation equations to address the issues encountered in haplotype-based pharmacogenetic analysis, including analysis of longitudinal data with outcome-dependent dropouts, and evaluation of the high-dimensional haplotype and haplotype-drug interaction effects in an overall manner. We use the inverse probability weights to handle the outcome-dependent...

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Identifiers

PMID: 20309762
DOI: 10.1080/10543400903572787
PMCID: PMC2845928

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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