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Article

Gene silencing for functional analysis: assessing RNAi as a tool for manipulation of gene expression.

Methods in molecular biology (Clifton, N.J.) - 1 Jan 2010

Ziv Carmit, Yarden Oded

Abstract excerpt

The availability of a large number of gene-disrupted mutants (either from natural mutants' collections or from knockout projects) is a great advantage for functional analysis studies. However, disfunction of many fungal genes, involved in key developmental processes, leads to dramatic and pleotropic changes in cell morphology, conferring a major difficulty in studying null mutants. Therefore, obtaining variable...

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PMID: 20238262
DOI: 10.1007/978-1-60761-611-5_6

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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