Article
Histone hyperacetylation affects meiotic recombination and chromosome segregation in Arabidopsis.
The Plant journal : for cell and molecular biology - 1 Jun 2010
Perrella Giorgio, Consiglio M Federica, Aiese-Cigliano Riccardo, Cremona Gaetana, Sanchez-Moran Eugenio, Barra Lucia, Errico Angela, Bressan Ray A, Franklin F Christopher H, Conicella Clara
Abstract excerpt
In this study, the meiotic role of MEIOTIC CONTROL OF CROSSOVERS1 (MCC1), a GCN5-related histone N-acetyltransferase, is described in Arabidopsis. Analysis of the over-expression mutant obtained by enhancer activation tagging revealed that acetylation of histone H3 increased in male prophase I. MCC1 appeared to be required in meiosis for normal chiasma number and distribution and for chromosome segregation....
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