Article
Mutant prevention concentrations of fluoroquinolones against Campylobacter jejuni isolated from chicken.
Veterinary microbiology - 26 Aug 2010
Wang Liping, Yuanshu Zhang, Yuhan Zhang, Yaojie, Yingxia Li
Abstract excerpt
The mutant prevention concentration (MPC) and mutant selection window (MSW) concepts have been used to evaluate antibiotic concentration ranges that prevent the emergence of antibiotic resistant mutants. Campylobacter jejuni is highly mutable to fluoroquinolone (FQ) antibiotics, but it is unknown if the MPC concept can be used to prevent mutant emergence. In this study, the MPCs of three FQs including...
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