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Hepatic Endoderm Differentiation from Human Embryonic Stem Cells

15 Jul 2010

Abstract excerpt

Primary human hepatocytes are a scarce resource with variable function which diminishes with time in culture. As a consequence their use in tissue modelling and therapy is restricted. Human embryonic stem cells (hESC) could provide a stable source of human tissue due to their properties of self-renewal and their ability to give rise to all three germ layers. hESCs have the potential to provide an unlimited supply...

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PMID: 20214561
DOI: 10.2174/157488810791824403

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