Article
Usher proteins in inner ear structure and function.
Physiological genomics - 1 Nov 2013
Ahmed Zubair M, Frolenkov Gregory I, Riazuddin Saima
Abstract excerpt
Usher syndrome (USH) is a neurosensory disorder affecting both hearing and vision in humans. Linkage studies of families of USH patients, studies in animals, and characterization of purified proteins have provided insight into the molecular mechanisms of hearing. To date, 11 USH proteins have been identified, and evidence suggests that all of them are crucial for the function of the mechanosensory cells of the...
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