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Article

Frequent promoter hypermethylation of the APC and RASSF1A tumour suppressors in parathyroid tumours.

PloS one - 1 Mar 2010

Juhlin C Christofer, Kiss Nimrod B, Villablanca Andrea, Haglund Felix, Nordenström Jörgen, Höög Anders, Larsson Catharina

Abstract excerpt

BACKGROUND: Parathyroid adenomas constitute the most common entity in primary hyperparathyroidism, and although recent advances have been made regarding the underlying genetic cause of these lesions, very little data on epigenetic alterations in this tumour type exists. In this study, we have determined the levels of promoter methylation regarding the four tumour suppressor genes APC, RASSF1A, p16(INK4A) and...

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Share to Adenomatous Polyposis Coli Protein

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Cyclin-Dependent Kinase Inhibitor p16

Share to Genes, APC

Share to Long Interspersed Nucleotide Elements

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Share to Receptors, Retinoic Acid

Source

Open in PubMed Open full text

Identifiers

PMID: 20208994
DOI: 10.1371/journal.pone.0009472
PMCID: PMC2830427

Genes

APC
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Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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