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Article

Association of the manganese superoxide dismutase polymorphism with vasospastic angina pectoris.

Journal of cardiology - 1 Mar 2010

Fujimoto Hajime, Kobayashi Hisae, Ogasawara Ken, Yamakado Minoru, Ohno Minoru

Abstract excerpt

BACKGROUND: Vasospastic angina (VSA) is closely related to endothelial dysfunction caused by oxidative damage. Manganese superoxide dismutase (MnSOD) is an antioxidant enzyme that functions in mitochondria. There are two genetic variants of MnSOD arising from a substitution of an alanine for a valine in the signal peptide. We previously reported that the valine allele of MnSOD decreases the mitochondrial MnSOD...

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PMID: 20206073
DOI: 10.1016/j.jjcc.2009.10.011

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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