Article
TRAF1/C5 polymorphism is not associated with increased mortality in rheumatoid arthritis: two large longitudinal studies.
Arthritis research & therapy - 1 Jan 2010
van Nies Jessica A B, Marques Rute B, Trompet Stella, de Jong Zuzana, Kurreeman Fina A S, Toes Rene E M, Jukema J Wouter, Huizinga Tom W J, van der Helm-van Mil Annette H M
Abstract excerpt
INTRODUCTION: Recently an association between a genetic variation in TRAF1/C5 and mortality from sepsis or cancer was found in rheumatoid arthritis (RA). The most prevalent cause of death, cardiovascular disease, may have been missed in that study, since patients were enrolled at an advanced disease stage. Therefore, we used an inception cohort of RA patients to investigate the association between TRAF1/C5 and...
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