Article
Lack of association between CYP21 V281L variant and polycystic ovary syndrome in Italian women.
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology - 1 Aug 2010
Pucci Laura, Lucchesi Daniela, Longo Vincenzo, Del Prato Stefano, Maffei Silvia
Abstract excerpt
AIM: To investigate the association between V281L CYP21 polymorphism and the hyperandrogenic phenotype of polycystic ovary syndrome (PCOS), in a cohort of 110 Italian women. METHODS: The CYP21 genotype distribution was evaluated in 50 women with PCOS and 60 control subjects. Genotypes were detected using restriction fragment length polymorphism (RFLP) analysis performed on polymerase chain reaction templates from...
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