Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The retinitis pigmentosa GTPase regulator interacting protein 1 (RPGRIP1) links RPGR to the nephronophthisis protein network.

Kidney international - 1 May 2010

Gerner Martin, Haribaskar Ramachandran, Pütz Michael, Czerwitzki Jacqueline, Walz Gerd, Schäfer Tobias

Abstract excerpt

Nephronophthisis is a heterogenetic autosomal recessive disorder associated with multiple developmental abnormalities, including cystic kidney disease and retinal degeneration. Retinal dystrophies, in particular the X-linked forms, are believed to represent a distinct group of hereditary diseases...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Eye Proteins
Share to RPGR gene
Share to GTP Phosphohydrolases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Mutation

Share to Proteins

Share to Retinitis Pigmentosa

Share to Zebrafish

Share to Zebrafish Proteins

Source

Identifiers

PMID: 20200501
DOI: 10.1038/ki.2010.27

Genes

RPGR
RPGRIP1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20200501-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The retinitis pigmentosa GTPase regulator interacting protein 1 (RPGRIP1) links RPGR to the nephronophthisis protein network.PMID 20200501Read ↗

The Role of RPGR and Its Interacting Proteins in CiliopathiesSemantic proximity Read ↗

Multiprotein complexes of Retinitis Pigmentosa GTPase regulator (RPGR), a ciliary protein mutated in X-linked Retinitis Pigmentosa (XLRP).Semantic proximity Read ↗

RPGR: Its role in photoreceptor physiology, human disease, and future therapiesSemantic proximity Read ↗

Human retinopathy-associated ciliary protein retinitis pigmentosa GTPase regulator mediates cilia-dependent vertebrate development.Semantic proximity Read ↗

RPGR: Role in the photoreceptor cilium, human retinal disease, and gene therapySemantic proximity Read ↗

Disease mechanisms of X-linked retinitis pigmentosa due to RP2 and RPGR mutations.Semantic proximity Read ↗

Zebrafish Rpgr is required for normal retinal development and plays a role in dynein-based retrograde transport processesSemantic proximity Read ↗

Nephrocystin-5, a ciliary IQ domain protein, is mutated in Senior-Loken syndrome and interacts with RPGR and calmodulin.Semantic proximity Read ↗

RPGR-containing protein complexes in syndromic and non-syndromic retinal degeneration due to ciliary dysfunction.Semantic proximity Read ↗

Retinitis Pigmentosa GTPase Regulator (RPGR)-interacting Protein Is Stably Associated with the Photoreceptor Ciliary Axoneme and Anchors RPGR to the Connecting CiliumSemantic proximity Read ↗

Genetic and physical interaction between the NPHP5 and NPHP6 gene products.Semantic proximity Read ↗

Interaction of nephrocystin-4 and RPGRIP1 is disrupted by nephronophthisis or Leber congenital amaurosis-associated mutations.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.