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Genetic vulnerability and phenotypic expression of depression and risk for ischemic heart disease in the Vietnam era twin study of aging.

Psychosomatic medicine - 1 May 2010

Xian Hong, Scherrer Jeffrey F, Franz Carol E, McCaffery Jeanne, Stein Phyllis K, Lyons Michael J, Jacobsen Kristen, Eisen Seth A, Kremen William S

Abstract excerpt

OBJECTIVE: To determine if depression contributes to incident heart disease after accounting for genetic, behavioral, and medical factors associated with both conditions. METHODS: We used a prospective twin study with a 12-year follow-up. In 1992, lifetime diagnosis of depression was assessed in 1159 male-male twins and merged with longitudinal health data from the Vietnam Era Twin Registry Study of Aging....

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Identifiers

PMID: 20190130
DOI: 10.1097/PSY.0b013e3181d28125
PMCID: PMC2874728

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