Common genetic liability to major depression and posttraumatic stress disorder in men.

doi:10.1016/j.jad.2007.04.021

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Article

Common genetic liability to major depression and posttraumatic stress disorder in men.

Journal of affective disorders - 1 Jan 2008

Koenen Karestan C, Fu Qiang J, Ertel Karen, Lyons Michael J, Eisen Seth A, True William R, Goldberg Jack, Tsuang Ming T

Abstract excerpt

BACKGROUND: Major depression (MD) and posttraumatic stress disorder (PTSD) are highly comorbid. The degree to which a common genetic liability explains the etiology of the MD-PTSD association has not been quantified and has important implications for research and prevention. METHODS: This paper presents an analysis of data from 6744 members of the Vietnam Era Twin Registry. MD and PTSD were assessed using the...

Topics

Adult
Comorbidity
Depressive Disorder, Major
Diagnostic and Statistical Manual of Mental Disorders
Environment
Genetic Predisposition to Disease
Humans
Life Change Events
Male
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Registries

Severity of Illness Index

Stress Disorders, Post-Traumatic

Twins

United States

Veterans

Vietnam Conflict

Source

Open in PubMed Open full text

Identifiers

PMID: 17540456
DOI: 10.1016/j.jad.2007.04.021
PMCID: PMC2254223

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