Article
Involvement of T-cell receptor-beta alterations in the development of otosclerosis linked to OTSC2.
Genes and immunity - 1 Apr 2010
Schrauwen I, Venken K, Vanderstraeten K, Thys M, Hendrickx J-J, Fransen E, Van Laer L, Govaerts P J, Verstreken M, Schatteman I, Stinissen P, Hellings N, Van Camp G
Abstract excerpt
Otosclerosis is a common form of hearing loss, characterized by disordered bone remodeling in the otic capsule. Within the otosclerotic foci, several immunocompetent cells and immune-modulating factors can be found. Different etiological theories involving the immune system have been suggested. H...
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