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Article

Genetic variants of the DDR1 gene are associated with vitiligo in two independent Brazilian population samples.

The Journal of investigative dermatology - 1 Jul 2010

Silva de Castro Caio Cesar, do Nascimento Liliane Machado, Walker Gaby, Werneck Renata Iani, Nogoceke Everson, Mira Marcelo Távora

Abstract excerpt

Vitiligo is a chronic disease characterized by macules devoid of melanin and identifiable melanocytes. Adhesion of melanocytes to the basement membrane by integrin CCN3 is mediated through collagen IV receptor DDR1. We hypothesize that genetic variants of the DDR1 gene are associated with the occurrence of vitiligo. To test this hypothesis, we genotyped 10 DDR1 tag single-nucleotide polymorphisms (SNPs) in 212...

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Source

Identifiers

PMID: 20182441
DOI: 10.1038/jid.2010.34

Genes

DDR1
CCN3

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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