Article
Variation in the mutagenic potential of acridines in Salmonella typhimurium, with stage of the culture.
Mutation research - 1 Apr 1991
Ferguson L R, Pogai H, Turner P M
Abstract excerpt
The mutagenic potential of proflavine differed by up to two orders of magnitude in three strains of Salmonella typhimurium carrying the frameshift marker hisC3076, depending upon the stage of the culture. In cultures at a specific stage, proflavine showed decreased mutagenesis in a recA as compared with a wildtupe or uvrB derivative. The related compound 9-aminoacridine also showed marked variation in mutagenic...
Topics
- Aminacrine
- Bacterial Proteins
- DNA Helicases
- Escherichia coli Proteins
- Genes, Bacterial
- Genetic Variation
- Mutagenicity Tests
- Proflavine
- Rec A Recombinases
- Salmonella typhimurium
