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Article

Molecular characterisation of trimethoprim resistance in Escherichia coli and Klebsiella pneumoniae during a two year intervention on trimethoprim use.

PloS one - 16 Feb 2010

Brolund Alma, Sundqvist Martin, Kahlmeter Gunnar, Grape Malin

Abstract excerpt

BACKGROUND: Trimethoprim resistance is increasing in Enterobacteriaceae. In 2004-2006 an intervention on trimethoprim use was conducted in Kronoberg County, Sweden, resulting in 85% reduction in trimethoprim prescriptions. We investigated the distribution of dihydrofolate reductase (dfr)-genes and integrons in Escherichia coli and Klebsiella pneumoniae and the effect of the intervention on this distribution....

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Identifiers

PMID: 20169085
DOI: 10.1371/journal.pone.0009233
PMCID: PMC2821933

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Source receipt: pubmed, retrieved 7 Sept 2026.

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