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Article

Transglutaminase1 preferred substrate peptide K5 is an efficient tool in diagnosis of lamellar ichthyosis.

The American journal of pathology - 1 Apr 2010

Akiyama Masashi, Sakai Kaori, Yanagi Teruki, Fukushima Satoshi, Ihn Hironobu, Hitomi Kiyotaka, Shimizu Hiroshi

Abstract excerpt

Lamellar ichthyosis (LI) is a genetically heterogeneous, severe genodermatosis showing widespread hyperkeratosis of the skin. Transglutaminase 1 (TGase1) deficiency by TGase1 gene (TGM1) mutations is the most prevalent cause of LI. Screening of TGase1 deficiency in skin is essential to facilitate...

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Source

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Identifiers

PMID: 20167857
DOI: 10.2353/ajpath.2010.090597
PMCID: PMC2843450

Genes

TGM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20167857-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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Transglutaminase1 preferred substrate peptide K5 is an efficient tool in diagnosis of lamellar ichthyosis.PMID 20167857Read ↗

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