Article
Should diffuse bronchiectasis still be considered a CFTR-related disorder?
Journal of cystic fibrosis : official journal of the European Cystic Fibrosis Society - 1 Sept 2015
Bergougnoux Anne, Viart Victoria, Miro Julie, Bommart Sébastien, Molinari Nicolas, des Georges Marie, Claustres Mireille, Chiron Raphaël, Taulan-Cadars Magali
Abstract excerpt
BACKGROUND: Although several comprehensive studies have evaluated the role of the CFTR gene in idiopathic diffuse bronchiectasis (DB), it remains controversial. METHODS: We analyzed the whole coding region of the CFTR gene, its flanking regions and the promoter in 47 DB patients and 47 controls. Available information about demographic, spirometric, radiological and microbiological data for the DB patients was...
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