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Article

Association of distinctive Epstein-Barr virus variants with gastric carcinoma in Guangzhou, southern China.

Journal of medical virology - 1 Apr 2010

Chen Jian-Ning, Ding Yun-Gang, Feng Zhi-Ying, Li Hai-Gang, He Dan, Du Hong, Wu Bin, Shao Chun-Kui

Abstract excerpt

To investigate the clinicopathologic features, Epstein-Barr virus (EBV) latency pattern and genome polymorphism of EBV-associated gastric carcinoma (EBVaGC) in Guangzhou, an endemic area of nasopharyngeal carcinoma (NPC), an in situ hybridization assay of EBV-encoded small RNA-1 (EBER-1) was used to identify the presence of EBV in 676 consecutive gastric carcinoma cases. EBV-encoded proteins EBNA1, EBNA2, LMP1,...

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PMID: 20166192
DOI: 10.1002/jmv.21731

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