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Article

Analytic validity of genetic tests to identify factor V Leiden and prothrombin G20210A.

American journal of hematology - 1 Apr 2010

Emadi Ashkan, Crim Matthew T, Brotman Daniel J, Necochea Alejandro J, Samal Lipika, Wilson Lisa M, Bass Eric B, Segal Jodi B

Abstract excerpt

The objective of this study is to systematically review methods for detecting Factor V Leiden or prothrombin G20210A. English-language literature from MEDLINE, EMBASE, The Cochrane Library, the Cumulative Index to Nursing and Allied Health Literature, PsycInfo(c), 2000-December 2008. Studies assessed methods for detection of these mutations in at least 10 human blood samples and reported concordance, discordance,...

Topics

Amino Acid Substitution
DNA Mutational Analysis
Factor V
Genetic Testing
Humans
Mutation
Prothrombin
Quality Assurance, Health Care
Reproducibility of Results
Sensitivity and Specificity

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Validation Studies as Topic

Source

Identifiers

PMID: 20162544
DOI: 10.1002/ajh.21617

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