Article
Predictive value of factor V Leiden and prothrombin G20210A in adults with venous thromboembolism and in family members of those with a mutation: a systematic review.
JAMA - 17 Jun 2009
Segal Jodi B, Brotman Daniel J, Necochea Alejandro J, Emadi Ashkan, Samal Lipika, Wilson Lisa M, Crim Matthew T, Bass Eric B
Abstract excerpt
CONTEXT: Testing for genetic risks for venous thromboembolism (VTE) is common, but the safety and utility of such testing need review. OBJECTIVES: To define rates of recurrent VTE among adults with VTE with a factor V Leiden (FVL) or prothrombin G20210A mutation compared with those without such mutations; to define rates of VTE among family members of adults with a FVL or prothrombin G20210A mutation according to...
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