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mTOR's role in ageing: protein synthesis or autophagy?

20 Jul 2009

Abstract excerpt

The molecular and cellular mechanisms that regulate ageing are currently under scrutiny because ageing is linked to many human diseases. The nutrient sensing TOR pathway is emerging as a key regulator of ageing. TOR signaling is complex affecting several crucial cellular functions and two such functions, which show clear effects on ageing, are protein synthesis and autophagy. In this article we discuss the...

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Autophagy in Disease and Therapy
Genetics, Aging, and Longevity in Model Organisms
Genomics, phytochemicals, and oxidative stress

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 20157541
DOI: 10.18632/aging.100070

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