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Article

Identification of a new lamin A/C mutation in a Chinese family affected with atrioventricular block as the prominent phenotype.

Journal of Huazhong University of Science and Technology. Medical sciences = Hua zhong ke ji da xue xue bao. Yi xue Ying De wen ban = Huazhong keji daxue xuebao. Yixue Yingdewen ban - 1 Feb 2010

Wu Xiaoyan, Wang Qing K, Gui Le, Liu Mugen, Zhang Xianqin, Jin Runming, Li Wei, Yan Lu, Du Rong, Wang Qiufen, Zhu Jianfang, Yang Junguo

Abstract excerpt

Even though mutations in LMNA have been reported in patients with typical dilated cardiomyopathy (DCM) and atrioventricular block (AVB) previously, the purpose of this study was to disclose this novel genetic abnormality in one Chinese family with the atypical phenotype of progressive AVB followed by DCM with normal QRS interval. Genome-wide linkage analysis mapped the AVB gene in this family to a marker at...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20155465
DOI: 10.1007/s11596-010-0119-z

Genes

LMNA

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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