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Article

Leptin receptor (LEPR) SNP polymorphisms in HELLP syndrome patients determined by quantitative real-time PCR and melting curve analysis.

BMC medical genetics - 11 Feb 2010

Várkonyi Tibor, Lázár Levente, Molvarec Attila, Than Nándor Gábor, Rigó János, Nagy Bálint

Abstract excerpt

BACKGROUND: Several studies have shown overexpression of leptin in microarray experiments in pre-eclampsia (PE) and in hemolysis, elevated liver enzymes, low platelets (HELLP) syndrome. We decided to study four leptin receptor (LEPR) SNP polymorphisms in HELLP syndrome patients by using quantitative real-time PCR and melting curve analysis. METHODS: DNA was isolated from blood samples from 83 normotensive...

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Identifiers

PMID: 20149225
DOI: 10.1186/1471-2350-11-25
PMCID: PMC2833147

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LEPR

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