Article
Leptin receptor (LEPR) SNP polymorphisms in HELLP syndrome patients determined by quantitative real-time PCR and melting curve analysis.
BMC medical genetics - 11 Feb 2010
Várkonyi Tibor, Lázár Levente, Molvarec Attila, Than Nándor Gábor, Rigó János, Nagy Bálint
Abstract excerpt
BACKGROUND: Several studies have shown overexpression of leptin in microarray experiments in pre-eclampsia (PE) and in hemolysis, elevated liver enzymes, low platelets (HELLP) syndrome. We decided to study four leptin receptor (LEPR) SNP polymorphisms in HELLP syndrome patients by using quantitat...
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