Article
Two novel SNPs of the ABCG2 gene and its associations with milk traits in Chinese Holsteins.
Molecular biology reports - 1 Jun 2011
Yue Wangping, Fang Xingtang, Zhang Chunlei, Pang Yonghong, Xu Haixia, Gu Chuanwen, Shao Ruying, Lei Chuzhao, Chen Hong
Abstract excerpt
The ATP-binding cassette transporter ABCG2 (also known as breast cancer resistance protein, BCRP) belongs to the ATP-binding cassette (ABC) family of transmembrane drug transporters, playing a crucial role in the protection of various cells and tissues against xenotoxins and/or endotoxins. Recently, several studies have proposed it as the potential gene underlying the QTL on bovine chromosome 6. Hence, in this...
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