Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Upper airway dysfunction of Tau-P301L mice correlates with tauopathy in midbrain and ponto-medullary brainstem nuclei.

The Journal of neuroscience : the official journal of the Society for Neuroscience - 3 Feb 2010

Dutschmann Mathias, Menuet Clement, Stettner Georg M, Gestreau Christian, Borghgraef Peter, Devijver Herman, Gielis Lies, Hilaire Gerard, Van Leuven Fred

Abstract excerpt

Tauopathy comprises hyperphosphorylation of the microtubule-associated protein tau, causing intracellular aggregation and accumulation as neurofibrillary tangles and neuropil treads. Some primary tauopathies are linked to mutations in the MAPT gene coding for protein tau, but most are sporadic wi...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aging
Share to Brain Stem
Share to Mesencephalon

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phosphorylation

Share to Pulmonary Ventilation

Share to Respiration Disorders

Share to tau Proteins

Share to Tauopathies

Source

Open in PubMed Open full text

Identifiers

PMID: 20130190
DOI: 10.1523/JNEUROSCI.5261-09.2010
PMCID: PMC6633985

Genes

MAPT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20130190-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Upper airway dysfunction of Tau-P301L mice correlates with tauopathy in midbrain and ponto-medullary brainstem nuclei.PMID 20130190Read ↗

Age-related impairment of ultrasonic vocalization in Tau.P301L mice: possible implication for progressive language disorders.Semantic proximity Read ↗

Targeted brain-specific tauopathy compromises peripheral skeletal muscle integrity and functionSemantic proximity Read ↗

A new physiologically realistic and clinically relevant model of sleep apnoea for investigating it’s effect as a comorbidity on neurodegenerative diseaseSemantic proximity Read ↗

Lower motor neuron disease with respiratory failure caused by a novel MAPT mutation.Semantic proximity Read ↗

Long-term proteasomal inhibition in transgenic mice by UBB(+1) expression results in dysfunction of central respiration control reminiscent of brainstem neuropathology in Alzheimer patients.Semantic proximity Read ↗

Pattern of tau hyperphosphorylation and neurotransmitter markers in the brainstem of senescent tau filament forming transgenic mice.Semantic proximity Read ↗

Postinspiratory complex acts as a gating mechanism regulating swallow-breathing coordination and other laryngeal behaviorsSemantic proximity Read ↗

Breathing dysfunction in Rett syndrome: understanding epigenetic regulation of the respiratory network.Semantic proximity Read ↗

Behavioural Functions and Cerebral Blood Flow in a P301S Tauopathy Mouse Model: A Time-Course Study.Semantic proximity Read ↗

Diffusion Tensor Imaging Reveals Whole-Brain Microstructural Changes in the P301L Mouse Model of TauopathySemantic proximity Read ↗

Tauopathy and alcohol consumption interact to alter locus coeruleus excitatory transmission and excitability in male and female miceSemantic proximity Read ↗

Neural basis for mutant ATAXIN-1 induced respiratory dysfunction in mouse models of spinocerebellar ataxia type 1.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.