Article
Brain white matter 1 H MRS in Leber optic neuropathy mutation carriers.
Acta neurologica Belgica - 1 Dec 2009
Ostojic Jelena, Jancic Jasna, Kozic Dusko, Semnic Robert, Koprivsek Katarina, Prvulovic Mladen, Kostic Vladimir
Abstract excerpt
OBJECTIVE: This study was conducted in order to test the hypothesis that proton MR spectroscopic (1H MRS) profile of Leber's hereditary optic neuropathy (LHON) mutation carriers group (including both symptomatic and asymptomatic) differs from group of healthy individuals and to determine metabolite or ratio that contributes most to differentiation. PATIENTS AND METHODS: We performed single voxel 1H MRS in normal...
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