Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Leber's optic neuropathy associated with disseminated white matter disease: a case report and review.

Clinical neurology and neurosurgery - 1 Jan 2009

Perez F, Anne O, Debruxelles S, Menegon P, Lambrecq V, Lacombe D, Martin-Negrier M L, Brochet B, Goizet C

Abstract excerpt

Leber's hereditary optic neuropathy (LHON), a mitochondrial disease, is clinically characterized by a bilateral subacute loss of central vision consecutive to optic nerve involvement. In some cases of LHON, neurological features are reported including multiple sclerosis-like (MSL) phenotype. We report one additional male patient displaying LHON-MSL associated with the prevalent G11778A mutation and review the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain
Share to DNA, Mitochondrial

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Magnetic Resonance Imaging

Share to Multiple Sclerosis

Share to Mutation

Share to Nerve Fibers, Myelinated

Share to Optic Atrophy, Hereditary, Leber

Source

Identifiers

PMID: 18848389
DOI: 10.1016/j.clineuro.2008.06.021

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Leber's optic neuropathy associated with disseminated white matter disease: a case report and review.PMID 18848389Read ↗

Leber’s hereditary optic neuropathy and multiple sclerosis: overlap between mitochondrial disease and neuroinflammationSemantic proximity Read ↗

Leber Hereditary Optic Neuropathy: A Mitochondrial Disease Unique in Many Ways.Semantic proximity Read ↗

Mitochondria in neuroinflammation - Multiple sclerosis (MS), leber hereditary optic neuropathy (LHON) and LHON-MS.Semantic proximity Read ↗

Multiple sclerosis associated with Leber's Hereditary Optic Neuropathy.Semantic proximity Read ↗

[Leber's optic neuropathy: a case report].Semantic proximity Read ↗

Leber's hereditary optic neuropathy associated with multiple sclerosis: Harding's syndrome.Semantic proximity Read ↗

[Leber's hereditary optic neuropathy].Semantic proximity Read ↗

Leber hereditary optic neuropathy, progressive visual loss, and multiple-sclerosis-like symptoms.Semantic proximity Read ↗

An Unusual Presentation of Leber Hereditary Optic Neuropathy-Plus Case Caused by a Novel DNAJC30 Variant.Semantic proximity Read ↗

Clinical features of MS associated with Leber hereditary optic neuropathy mtDNA mutations.Semantic proximity Read ↗

Late-onset progressive visual loss in a man with unusual MRI findings: MS, Harding's, Leber's or Leber's Plus?Semantic proximity Read ↗

Late-onset Leber's hereditary optic neuropathy presenting with longitudinally extensive myelitis harbouring the m.14484T>C mutation: Extending the genotype-phenotype spectrum.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.