Article
CYP2C9 genotype does not affect risk of tobacco-related cancer in the general population.
Cancer epidemiology - 1 Apr 2010
Kaur-Knudsen Diljit, Nordestgaard Børge Grønne, Bojesen Stig Egil
Abstract excerpt
BACKGROUND: CYP2C9 enzymes are important in the metabolism of procarcinogenic chemicals such as polycyclic aromatic hydrocarbons (PAHs) found in tobacco smoke. Two functional variants in the CYP2C9 gene (CYP2C9*2 and CYP2C9*3) are known to be associated with decreased enzyme activity towards tolb...
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