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Article

CYP2C9 genotype does not affect risk of tobacco-related cancer in the general population.

Cancer epidemiology - 1 Apr 2010

Kaur-Knudsen Diljit, Nordestgaard Børge Grønne, Bojesen Stig Egil

Abstract excerpt

BACKGROUND: CYP2C9 enzymes are important in the metabolism of procarcinogenic chemicals such as polycyclic aromatic hydrocarbons (PAHs) found in tobacco smoke. Two functional variants in the CYP2C9 gene (CYP2C9*2 and CYP2C9*3) are known to be associated with decreased enzyme activity towards tolbutamide and warfarin, while this has not been investigated for PAHs. We hypothesised that these two variants in the...

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Identifiers

PMID: 20117066
DOI: 10.1016/j.canep.2010.01.003

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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