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Article

Thyroidectomies from patients with history of therapeutic radiation during childhood and adolescence have a unique mutational profile.

Modern pathology : an official journal of the United States and Canadian Academy of Pathology, Inc - 1 Sept 2008

Assaad Adel, Voeghtly Laura, Hunt Jennifer L

Abstract excerpt

Radiation in childhood is a known risk factor for thyroid carcinoma, but may also be related to benign nodular hyperplasias. Recent evidence from comparative genomic hybridization indicates that radiation can induce clonal DNA damage in cultured rat thyrocytes. We used a loss of heterozygosity analysis for the loci identified by comparative genomic hybridization to study human thyroids. Thyroids from patients...

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Source

Identifiers

PMID: 18587320
DOI: 10.1038/modpathol.2008.122

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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