Article
CYP17 and CYP2C19 gene polymorphisms in patients with endometriosis.
Reproductive biomedicine online - 1 Feb 2010
Bozdag Gurkan, Alp Alpaslan, Saribas Zeynep, Tuncer Selcuk, Aksu Tarik, Gurgan Timur
Abstract excerpt
Endometriosis seems to be the result of a complex interaction between environmental factors and various genes. In this regard, the cytochrome subfamily 17 (CYP17) may play an important role by altering the biosynthesis of sex steroids. CYP2C19 is also an important member of the cytochrome P450 (CYP) family, and related mutations may result in an inability to fully metabolize environmental chemicals and cytokines,...
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