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Article

Novel inhibitors of dengue virus methyltransferase: discovery by in vitro-driven virtual screening on a desktop computer grid.

Journal of medicinal chemistry - 25 Feb 2010

Podvinec Michael, Lim Siew Pheng, Schmidt Tobias, Scarsi Marco, Wen Daying, Sonntag Louis-Sebastian, Sanschagrin Paul, Shenkin Peter S, Schwede Torsten

Abstract excerpt

Dengue fever is a viral disease that affects 50-100 million people annually and is one of the most important emerging infectious diseases in many areas of the world. Currently, neither specific drugs nor vaccines are available. Here, we report on the discovery of new inhibitors of the viral NS5 R...

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Source

Identifiers

PMID: 20108931
DOI: 10.1021/jm900776m

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20108931-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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