Article
A genetic screen for modifiers of Drosophila caspase Dcp-1 reveals caspase involvement in autophagy and novel caspase-related genes.
BMC cell biology - 25 Jan 2010
Kim Young-Il, Ryu Taewoo, Lee Judong, Heo Young-Shin, Ahnn Joohong, Lee Seung-Jae, Yoo OokJoon
Abstract excerpt
BACKGROUND: Caspases are cysteine proteases with essential functions in the apoptotic pathway; their proteolytic activity toward various substrates is associated with the morphological changes of cells. Recent reports have described non-apoptotic functions of caspases, including autophagy. In thi...
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