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Article

Upregulation of REG Iα accelerates tumor progression in pancreatic cancer with diabetes

22 Jan 2010

Abstract excerpt

Diabetes is now generally accepted as a crucial event in the process of pancreatic cancer (PaC). However, molecular mechanisms underlying the relationship between diabetes and PaC are not fully understood. Regenerating gene (REG) Ialpha is a growth factor affecting pancreatic islet beta cells, and it has been shown to be involved in the carcinogenesis in gastrointestinal tract. It is rational to speculate that...

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Identifiers

PMID: 20099282
DOI: 10.1002/ijc.25188

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Related research

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Research trail→

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Upregulation of REG Iα accelerates tumor progression in pancreatic cancer with diabetesPMID 20099282Read ↗

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Implication of Reg I in human pancreatic duct-like cells in vivo in the pathological pancreas and in vitro during exocrine dedifferentiation.Semantic proximity Read ↗

Synergistic Activations of<i>REG I<b><i>α</i></b></i>and<i>REG I</i><b><i>β</i></b>Promoters by IL-6 and Glucocorticoids through JAK/STAT Pathway in Human Pancreatic<b><i>β</i></b>CellsSemantic proximity Read ↗

REG4 independently predicts better prognosis in non-mucinous colorectal cancer.Semantic proximity Read ↗

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