Article
Ventricular rotation is independent of cardiac looping: a study in mice with situs inversus totalis using speckle-tracking echocardiography.
Journal of the American Society of Echocardiography : official publication of the American Society of Echocardiography - 1 Mar 2010
Frank Lowell H, Yu Qing, Francis Richard, Tian Xin, Samtani Rajeev, Sahn David J, Leatherbury Linda, Lo Cecilia W
Abstract excerpt
BACKGROUND: The authors conducted an ultrasound interrogation of a mutant mouse model with a Dnah5 mutation to determine whether cardiac mechanics may be affected by reversal of cardiac situs. This mutant is a bona fide model of primary ciliary dyskinesia, with surviving homozygous mice showing either situs solitus (SS) or situs inversus totalis (SI). METHODS: High-frequency ultrasound interrogations of 27...
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