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Article

Variation in the CBP gene involved in epigenetic control associates with cognitive function.

Neurobiology of aging - 1 Mar 2011

Trompet Stella, de Craen Anton J M, Jukema J Wouter, Pons D, Slagboom P Eline, Kremer D, Bollen Eduard L E M, Westendorp Rudi G J

Abstract excerpt

Research into the pathologic mechanisms of neurodegenerative diseases has revealed that CREB binding protein (CBP) plays an important role in cognitive dysfunction. Loss of one copy of this gene leads to a syndrome with severe cognitive dysfunction. We investigated the association between four common variants in the CBP gene and cognitive function in 5804 participants of the PROspective Study of Pravastatin in...

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Identifiers

PMID: 20096957
DOI: 10.1016/j.neurobiolaging.2009.12.019

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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