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Article

Aberrant expression of the neuronal transcription factor FOXP2 in neoplastic plasma cells

21 Jan 2010

Abstract excerpt

FOXP2 mutation causes a severe inherited speech and language defect, while the related transcription factors FOXP1, FOXP3 and FOXP4 are implicated in cancer. FOXP2 mRNA and protein expression were characterised in normal human tissues, haematological cell lines and multiple myeloma (MM) patients' samples. FOXP2 mRNA and protein were absent in mononuclear cells from different anatomical sites, lineages and stages...

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PMID: 20096010
DOI: 10.1111/j.1365-2141.2009.08070.x

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